It has a wide variety of art styles and more variation in subject matter, ranging from the avant-garde to the pornographic. Seinen manga is distinguished from shōnen, or boys' manga, by having a stronger emphasis on realism. Because of the emphasis on storyline and character development instead of action, some seinen series are often confused with shōjo, or girls' manga. This is especially true of seinen comedy series such as Chobits, and Chi's Sweet Home, or seinen drama such as Twin Spica. Other examples of seinen manga include: Gantz, Battle Royale, 20th Century Boys, Monster, Blame!, Ghost in the Shell, Akira, Berserk, Battle Angel Alita, Hellsing, Neon Genesis Evangelion, Elfen Lied, and Maison Ikkoku.
A common way to tell if a manga is seinen is by looking at whether or not furigana is used over the original kanji text: if there are furigana on all kanji, the title is generally aimed at a younger audience. The title of the magazine it was published in is also an important indicator. Usually Japanese manga magazines with the word "young" in the title (Weekly Young Jump for instance) are seinen. Other popular seinen manga magazines include Ultra Jump, Afternoon, and Big Comic.